Article
Rat mitochondrial aldehyde dehydrogenase polymorphism and major histocompatibility complex RT1.A phenotypes are not associated with alcohol drinking in P and NP rats.
Alcoholism, clinical and experimental research - 1 Apr 1995
Carr L G, Kirchner J, Magnes L, Lumeng L, Li T K
Abstract excerpt
Previous studies revealed polymorphisms in mitochondrial aldehyde dehydrogenase (ALDH2) and the major histocompatibility complex RT1.A that appeared in association with alcohol drinking preference in the alcohol-preferring (P) and alcohol-nonpreferring (NP) rat lines. To determine the strength of...
Topics
- Alcohol Drinking
- Alcoholism
- Aldehyde Dehydrogenase
- Alleles
- Animals
- Female
- Gene Expression Regulation, Enzymologic
- Histocompatibility Antigens
- Isoenzymes
- Major Histocompatibility Complex
- Male
- Mitochondria, Liver
- Phenotype
- Polymorphism, Genetic
- Rats
- Rats, Inbred Strains