Article
Complex I regulates mutant mitochondrial aldehyde dehydrogenase activity and voluntary ethanol consumption in rats.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jan 2005
Quintanilla María Elena, Tampier Lutske, Valle-Prieto Araceli, Sapag Amalia, Israel Yedy
Abstract excerpt
Animals selectively bred for a desirable trait retain wanted genes but exclude genes that may counteract the expression of the former. The possible interactions between selected and excluded genes cannot be readily studied in transgenic or knockout animals but may be addressed by crossing animals bred for opposite traits and studying the F2 offspring. Ninety-seven percent of Wistar-derived rats selectively bred...
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