Article
Fission yeast TPR-family protein nuc2 is required for G1-arrest upon nitrogen starvation and is an inhibitor of septum formation.
Journal of cell science - 1 Mar 1995
Kumada K, Su S, Yanagida M, Toda T
Abstract excerpt
Fission yeast nuc2+ gene encodes a protein of a tetratricopeptide repeat (TPR) family which is conserved throughout evolution. We previously showed that nuc2 is required for exit from the mitotic metaphase. In this study, we present evidence which shows that nuc2 has two additional roles in the cell cycle. We showed that the nuc2 mutant is sterile even at the permissive temperature and septation occurs in the...
Topics
- Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome
- Base Sequence
- Cell Division
- DNA Primers
- DNA Replication
- Fungal Proteins
- G1 Phase
- G2 Phase
- Gene Expression
- Mating Factor
- Molecular Sequence Data