Article
Transcriptional changes in the nuc-2A mutant strain of Neurospora crassa cultivated under conditions of phosphate shortage.
Microbiological research - 1 Jan 2009
Gras Diana E, Silveira Henrique C S, Peres Nalu T A, Sanches Pablo R, Martinez-Rossi Nilce M, Rossi Antonio
Abstract excerpt
The molecular mechanism that controls the response to phosphate shortage in Neurospora crassa involves four regulatory genes -nuc-2, preg, pgov, and nuc-1. Phosphate shortage is sensed by the nuc-2 gene, the product of which inhibits the functioning of the PREG-PGOV complex. This allows the translocation of the transcriptional factor NUC-1 into the nucleus, which activates the transcription of...
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