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Article

Characterization of novel ligands for wild-type and natural mutant diazepam-insensitive benzodiazepine receptors.

European journal of pharmacology - 28 Apr 1995

Wong G, Uusi-Oukari M, Hansen H C, Suzdak P D, Korpi E R

Abstract excerpt

A series of benzodiazepine receptor ligands with different chemical structures were evaluated for their affinities at diazepam-sensitive and diazepam-insensitive binding sites for [3H]Ro 15-4513 (ethyl-8-azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazo-[1,5a][1,4] benzodiazepine-3-carboxylate) in cerebellar GABAA receptors. Rats of Wistar strain and of alcohol-sensitive (ANT) and alcohol-insensitive (AT) lines were...

Topics

Animals
Azides
Benzodiazepines
Binding, Competitive
Cerebellum
Diazepam
Ethanol
Male
Mutation
Rats
Rats, Wistar
Receptors, GABA-A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7621907
DOI: 10.1016/0922-4106(95)90111-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7621907-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Characterization of novel ligands for wild-type and natural mutant diazepam-insensitive benzodiazepine receptors.PMID 7621907Read ↗

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