Specific alterations in the cerebellar GABA(A) receptors of an alcohol-sensitive ANT rat line.

doi:10.1111/j.1530-0277.1991.tb01864.x

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Article

Specific alterations in the cerebellar GABA(A) receptors of an alcohol-sensitive ANT rat line.

Alcoholism, clinical and experimental research - 1 Mar 1991

Uusi-Oukari M, Korpi E R

Abstract excerpt

The AT (alcohol-tolerant) and ANT (alcohol-nontolerant) rat lines, selected for differential sensitivity to the acute motor-impairing effects of ethanol, have been shown to differ in the ligand binding characteristics of their cerebellar GABAA receptors. In the present study, we characterized the...

Topics

Alcohol Drinking
Animals
Arousal
Benzodiazepines
Cerebellum
Male
Muscimol
Olfactory Bulb
Phenotype
Rats
Rats, Inbred Strains
Receptors, GABA-A
Selection, Genetic

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