Article
CRP2 (C/EBP beta) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity.
The EMBO journal - 3 Jul 1995
Williams S C, Baer M, Dillner A J, Johnson P F
Abstract excerpt
Two members of the C/EBP family of basic region-leucine zipper proteins enriched in the liver, C/EBP (C/EBP alpha) and CRP2 (C/EBP beta), were previously shown to transactivate the albumin promoter in a cell type-dependent manner. These proteins function efficiently in HepG2 hepatoma cells, but i...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- CCAAT-Enhancer-Binding Proteins
- Carcinoma, Hepatocellular
- Chromosome Mapping
- DNA-Binding Proteins
- Genes, Regulator
- HeLa Cells
- Humans
- L Cells
- Leucine Zippers
- Liver
- Mice
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
