Article
Syncytium forming capacity of HIV 1 strains in inhibited by pretreatment of CD4 expressing cells with 3'-azido-3'-deoxythymidine but not by alpha interferon.
Revue roumaine de virologie (Bucharest, Romania : 1990) - 1 Jan 2000
Ruţă S M, Cernescu C
Abstract excerpt
3'azido-3'deoxythymidine (AZT) inhibits the ability of uninfected CD4 expressing cells to participate in syncytium formation, when cocultured with cells chronically infected with human immunodeficiency virus type 1 (HIV 1). The inhibition of giant cells formation is similar, irrespective of the A...
Topics
- CD4-Positive T-Lymphocytes
- Cell Fusion
- Giant Cells
- HIV-1
- HeLa Cells
- Humans
- Interferon-alpha
- Kinetics
- Phenotype
- Sensitivity and Specificity
- Zidovudine