Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Syncytium forming capacity of HIV 1 strains in inhibited by pretreatment of CD4 expressing cells with 3'-azido-3'-deoxythymidine but not by alpha interferon.

Revue roumaine de virologie (Bucharest, Romania : 1990) - 1 Jan 2000

Ruţă S M, Cernescu C

Abstract excerpt

3'azido-3'deoxythymidine (AZT) inhibits the ability of uninfected CD4 expressing cells to participate in syncytium formation, when cocultured with cells chronically infected with human immunodeficiency virus type 1 (HIV 1). The inhibition of giant cells formation is similar, irrespective of the AZT-sensitive or resistant phenotype of the HIV1 strains. The effect on syncytium formation occurs when the uninfected...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD4-Positive T-Lymphocytes
Share to Cell Fusion

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HeLa Cells

Share to Interferon-alpha

Share to Kinetics

Share to Phenotype

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 7619738

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Syncytium forming capacity of HIV 1 strains in inhibited by pretreatment of CD4 expressing cells with 3'-azido-3'-deoxythymidine but not by alpha interferon.PMID 7619738Read ↗

Human immunodeficiency virus type 1 clones chimeric for the envelope V3 domain differ in syncytium formation and replication capacity.Semantic proximity Read ↗

Acquisition of syncytium-inducing HIV-1 strains during therapy with zidovudine alone or combined with alpha interferon or didanosine.Semantic proximity Read ↗

Experimental HIV infection of human lymphoid tissue: correlation of CD4+ T cell depletion and virus syncytium-inducing/non-syncytium-inducing phenotype in histocultures inoculated with laboratory strains and patient isolates of HIV type 1.Semantic proximity Read ↗

[Replicative properties of HIV-1 strains, resistant to 3'-azido-2'3'-dideoxythymidine].Semantic proximity Read ↗

Fusion from without directed by human immunodeficiency virus particlesSemantic proximity Read ↗

Non-syncytium-inducing HIV type 1 isolated from infected individuals replicates in MT-2 cells.Semantic proximity Read ↗

Coexistence of fusion receptors for human T-cell leukemia virus type-I (HTLV-I) and human immunodeficiency virus type-1 (HIV-1) on MOLT-4 cells.Semantic proximity Read ↗

In vitro selection of variants of herpes simplex virus type 1 which differ in cytopathic changes.Semantic proximity Read ↗

Inhibition by AZT of HIV-1 replication in acutely infected U-937 cells.Semantic proximity Read ↗

Effect of Evans blue and trypan blue on syncytia formation and infectivity of human immunodeficiency virus type I and type II in vitro.Semantic proximity Read ↗

Combination of whole blood culture and a rapid and sensitive cell assay for the determination of the cytopathogenicity of human immunodeficiency virus type-1 isolates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.