Article
Effect of Evans blue and trypan blue on syncytia formation and infectivity of human immunodeficiency virus type I and type II in vitro.
AIDS research and human retroviruses - 1 Jun 1991
Pal R, Mumbauer S, Hoke G, Larocca R, Myers C, Sarngadharan M G, Stein C A
Abstract excerpt
Polyanionic compounds were used to inhibit infectivity of human immunodeficiency virus in vitro. Suramin, Evans blue, and Trypan blue were shown to inhibit syncytia formation normally observed when HIV-1-infected cells are cocultured with CD4+ cells. The inhibition was more pronounced with Evans...
Topics
- Antiviral Agents
- Cell Fusion
- Evans Blue
- HIV Reverse Transcriptase
- HIV-1
- HIV-2
- Humans
- Molecular Structure
- Mutation
- RNA-Directed DNA Polymerase
- Trypan Blue
- Tumor Cells, Cultured