Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combination of whole blood culture and a rapid and sensitive cell assay for the determination of the cytopathogenicity of human immunodeficiency virus type-1 isolates.

Journal of virological methods - 1 Mar 1998

Benyoucef S, Hober D, Lion G, Vilain V, Bocket L, Gérard Y, Wattré P

Abstract excerpt

It has been reported that in vitro biological properties of human immunodeficiency virus type 1 (HIV-1) isolates from patients are correlated with the prognosis of HIV-1 infection. A rapid assay was developed to study the phenotype of HIV-1 isolates. The P4 cell line is a HIV-1 infectible Hela CD4 cell carrying the bacterial LacZ gene under the control of the HIV-1 LTR (long terminal repeat). Conventional...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Cytopathogenic Effect, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Giant Cells

Share to Leukocytes, Mononuclear

Share to Phenotype

Share to Sensitivity and Specificity

Share to Virus Replication

Source

Identifiers

PMID: 9628228
DOI: 10.1016/s0166-0934(97)00210-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Combination of whole blood culture and a rapid and sensitive cell assay for the determination of the cytopathogenicity of human immunodeficiency virus type-1 isolates.PMID 9628228Read ↗

Imbalance in cytokine production by whole blood related to presence of cytopathogenic HIV-1 strains in HIV-1-infected patients.Semantic proximity Read ↗

Role of HIV-1 phenotype in viral pathogenesis and its relation to viral load and CD4+ T-cell count.Semantic proximity Read ↗

Cloning and characterization of human immunodeficiency virus type 1 variants diminished in the ability to induce syncytium-independent cytolysis.Semantic proximity Read ↗

Cytopathicity of Human Immunodeficiency Virus Type 2 (HIV-2) in Human Lymphoid Tissue Is Coreceptor Dependent and Comparable to That of HIV-1Semantic proximity Read ↗

Production of TNFalpha and IL-6 by activated whole blood from HIV-1 infected patients detected by a one-stage procedure: relationship with the phenotype of HIV-1 isolates.Semantic proximity Read ↗

Molecular determinants of acute single-cell lysis by human immunodeficiency virus type 1.Semantic proximity Read ↗

HIV1 cytopathogenicity-genetic difference between direct cytotoxic and fusogenic effect.Semantic proximity Read ↗

Importance of method in the determination of syncytium-inducing phenotype of human immunodeficiency virus type 1 clinical isolates.Semantic proximity Read ↗

Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase geneSemantic proximity Read ↗

Syncytium forming capacity of HIV 1 strains in inhibited by pretreatment of CD4 expressing cells with 3'-azido-3'-deoxythymidine but not by alpha interferon.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.