Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acquisition of syncytium-inducing HIV-1 strains during therapy with zidovudine alone or combined with alpha interferon or didanosine.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Apr 1996

Torres Y, Leal M, Rey C, Medrano F J, Sánchez-Quijano A, Lissen E

Abstract excerpt

The effect of antiretroviral treatment on HIV-1 phenotype was studied in a group of 83 nucleoside-naive patients. These initially nonsyncytium-inducing HIV-1 positive patients were followed prospectively for their HIV-1 phenotype. Syncytium-inducing variants were detected by cocultivation of peripheral blood mononuclear cells with the MT-2 T-cell line. Overall, 16 of 83 (19%) patients underwent a shift to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Drug Therapy, Combination

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Giant Cells

Share to HIV Infections

Share to Interferon-alpha

Share to Phenotype

Share to Zidovudine

Source

Identifiers

PMID: 8781884
DOI: 10.1007/BF01695665

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acquisition of syncytium-inducing HIV-1 strains during therapy with zidovudine alone or combined with alpha interferon or didanosine.PMID 8781884Read ↗

Evidence for differences in MT2 cell tropism according to genetic subtypes of HIV-1: syncytium-inducing variants seem rare among subtype C HIV-1 viruses.Semantic proximity Read ↗

Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS.Semantic proximity Read ↗

Association of syncytium-inducing phenotype of HIV-1 with CD4 cell count, viral load and sociodemographic characteristics.Semantic proximity Read ↗

Non-syncytium-inducing HIV type 1 isolated from infected individuals replicates in MT-2 cells.Semantic proximity Read ↗

Evolution of syncytium-inducing and non-syncytium-inducing biological virus clones in relation to replication kinetics during the course of human immunodeficiency virus type 1 infection.Semantic proximity Read ↗

HIV-1 viraemia changes in patients with and without syncytium-inducing phenotype treated with nucleoside analogues: a case-control study.Semantic proximity Read ↗

Phenotypic switch in a Spanish HIV type 1 isolate on serial passage on MT-4 cells.Semantic proximity Read ↗

Viral phenotype, antiretroviral resistance and clinical evolution in human immunodeficiency virus-infected children.Semantic proximity Read ↗

Completion of nucleotide sequences of non-syncytium-inducing and syncytium-inducing HIV type 1 variants isolated from the same patient.Semantic proximity Read ↗

Importance of method in the determination of syncytium-inducing phenotype of human immunodeficiency virus type 1 clinical isolates.Semantic proximity Read ↗

Maintenance of syncytium-inducing phenotype of HIV type 1 is associated with positively charged residues in the HIV type 1 gp120 V2 domain without fixed positions, elongation, or relocated N-linked glycosylation sites.Semantic proximity Read ↗

Role of HIV-1 phenotype in viral pathogenesis and its relation to viral load and CD4+ T-cell count.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.