Article
Acquisition of syncytium-inducing HIV-1 strains during therapy with zidovudine alone or combined with alpha interferon or didanosine.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Apr 1996
Torres Y, Leal M, Rey C, Medrano F J, Sánchez-Quijano A, Lissen E
Abstract excerpt
The effect of antiretroviral treatment on HIV-1 phenotype was studied in a group of 83 nucleoside-naive patients. These initially nonsyncytium-inducing HIV-1 positive patients were followed prospectively for their HIV-1 phenotype. Syncytium-inducing variants were detected by cocultivation of peri...
Topics
- Adult
- Anti-HIV Agents
- CD4 Lymphocyte Count
- Didanosine
- Drug Therapy, Combination
- Female
- Giant Cells
- HIV Infections
- HIV-1
- Humans
- Interferon-alpha
- Male
- Phenotype
- Prospective Studies
- Zidovudine