Article
Structural and functional analyses of DNA bending induced by Sp1 family transcription factors.
Journal of molecular biology - 4 Apr 1997
Sjøttem E, Andersen C, Johansen T
Abstract excerpt
DNA bending induced by eukaryotic transcription factors may play a direct role in the activation of transcription by bringing together factors bound at non-adjacent sites or facilitate binding of factors involved in the formation of an initiation complex. The ubiquitously expressed zinc-finger transcription factor Sp1 is involved in the regulation of a variety of viral and cellular genes. During the past few...
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