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Article

P53 germ line haplotypes associated with increased risk for colorectal cancer.

Carcinogenesis - 1 Jul 1995

Själander A, Birgander R, Athlin L, Stenling R, Rutegård J, Beckman L, Beckman G

Abstract excerpt

Three p53 DNA polymorphisms (BstU I and Msp I restriction fragment length polymorphisms (RFLPs) in exon 4 and intron 6 respectively, and a 16 bp duplication in intron 3) and their haplotype combinations were studied in patients with colorectal cancer and compared with patients with ulcerative colitis and healthy controls. There were only minor differences between patients with ulcerative colitis and controls, the...

Topics

Alleles
Base Sequence
Codon
Colitis, Ulcerative
Colorectal Neoplasms
DNA, Neoplasm
Genes, p53
Genotype
Germ-Line Mutation
Haplotypes
Humans
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Risk Factors

Source

Identifiers

PMID: 7614678
DOI: 10.1093/carcin/16.7.1461

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7614678-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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