Article
p53 polymorphisms and haplotypes in nasopharyngeal cancer.
Human heredity - 1 Jan 2000
Birgander R, Själander A, Zhou Z, Fan C, Beckman L, Beckman G
Abstract excerpt
Three p53 DNA polymorphisms (BstUI and MspI RFLPs in exon 4 and intron 6, respectively, and a 16-bp duplication in intron 3) and their haplotype combinations were studied in 73 patients (61 males and 12 females) with nasopharyngeal cancer and 105 healthy controls from the Guizhou province in southern China. Increased frequencies of the 16-bp A2 allele (p = 0.005), MspI A1 allele (p = 0.021) and the BstUI A1 (Pro)...
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