Article
The TP53 16-bp duplication polymorphism is enriched in endometriosis patients.
Gynecologic and obstetric investigation - 1 Jan 2012
Gallegos-Arreola M P, Valencia-Rodríguez L E, Puebla-Pérez A M, Figuera L E, Zúñiga-González G M
Abstract excerpt
BACKGROUND/AIM: The TP53 tumor suppressor gene encodes the nuclear phosphoprotein p53, which plays an important role in cell cycle regulation, apoptosis, DNA repair and angiogenesis. The TP53 gene contains common genetic polymorphisms that influence gene activity. Clinical implications of TP53 polymorphisms have been reported for several diseases, including a variety of solid tumors and endometriosis. We...
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