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Article

Interaction of human immunodeficiency virus type 1 Tat-derived peptides with TAR RNA.

Biochemistry - 11 Jul 1995

Long K S, Crothers D M

Abstract excerpt

Basic peptides from the carboxy terminus of the human immunodeficiency virus type 1 (HIV-1) Tat protein bind to the stem-loop region of TAR RNA, spanning a trinucleotide bulge, with high affinity and moderate specificity. Previous studies have demonstrated that TAR RNA contains a specific arginine binding pocket. A series of 24 amino acid Tat-derived peptides with one or two arginines has been evaluated as...

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Identifiers

PMID: 7612630
DOI: 10.1021/bi00027a041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interaction of human immunodeficiency virus type 1 Tat-derived peptides with TAR RNA.PMID 7612630Read ↗

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