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Article

Fluorescence correlation spectroscopy at single molecule level on the Tat-TAR complex and its inhibitors.

Biopolymers - 1 Jan 2008

Nandi Chayan Kanti, Parui Partha Pratim, Brutschy Bernhard, Scheffer Ute, Göbel Michael

Abstract excerpt

The TAR element of HIV and the viral protein Tat form a molecular switch regulating transcriptional efficiency in HIV. We show that fluorescence correlation spectroscopy at the single molecule level is a powerful method to study the association between a Tat-derived peptide and TAR fragments. We also investigated the inhibition of the peptide-RNA complex by different ligands. Utilizing cross correlation...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17764074
DOI: 10.1002/bip.20835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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