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Article

Binding sites of the viral RNA element TAR and of TAR mutants for various peptide ligands, probed with LILBID: a new laser mass spectrometry.

Journal of the American Society for Mass Spectrometry - 1 Nov 2008

Morgner Nina, Barth Hans-Dieter, Brutschy Bernhard, Scheffer Ute, Breitung Sven, Göbel Michael

Abstract excerpt

A new laser-based mass spectrometry method, called laser induced liquid bead ion desorption (LILBID), was applied to investigate RNA:ligand interactions. As model system the HIV Tat:TAR transactivation complex and its binding behavior were analyzed. TARwt of HIV Type 1 and Type 2 and different artificial mutants were compared regarding their binding to Tat and different peptide ligands. Specific and nonspecific...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to RNA, Viral

Share to tat Gene Products, Human Immunodeficiency Virus

Source

Identifiers

PMID: 18693035
DOI: 10.1016/j.jasms.2008.07.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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