Base-pairing interactions involving the 5' and 3'-terminal nucleotides of group II self-splicing introns.

doi:10.1016/S0022-2836(05)80206-2

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Article

Base-pairing interactions involving the 5' and 3'-terminal nucleotides of group II self-splicing introns.

Journal of molecular biology - 5 Jun 1990

Jacquier A, Michel F

Abstract excerpt

By combining comparative sequence analyses and nucleotide replacements, we show that formation of the active center of group II introns rests in part on two novel long-range base-pairing interactions. (1) The last nucleotide of group II introns forms a solitary Watson-Crick base-pair with one of...

Topics

Bacteriophages
Base Composition
Base Sequence
Genes, Regulator
Introns
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Poly A
RNA Caps
RNA Splicing
RNA, Catalytic
RNA, Ribosomal
Terminator Regions, Genetic

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