Phylogenetic and genetic evidence for base-triples in the catalytic domain of group I introns.

doi:10.1038/347578a0

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Article

Phylogenetic and genetic evidence for base-triples in the catalytic domain of group I introns.

Nature - 11 Oct 1990

Michel F, Ellington A D, Couture S, Szostak J W

Abstract excerpt

Understanding the mechanisms by which ribozymes catalyse chemical reactions requires a detailed knowledge of their structure. The secondary structure of the group I introns has been confirmed by comparison of over 70 published sequences, by chemical protection studies, and by genetic experiments...

Topics

Animals
Base Composition
Base Sequence
Binding Sites
Biological Evolution
Catalysis
Genetic Variation
Hydrogen Bonding
Introns
Molecular Sequence Data
Molecular Structure
Phylogeny
RNA, Catalytic
T-Phages
Tetrahymena

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