Article
Differential expression of HLA-DQB1 alleles in a heterozygous cell line.
Immunogenetics - 1 Jan 1995
Nepom G T, Chung J, West K A
Abstract excerpt
Regulation of HLA class II transcription is complex, with both locus-specific and allele-specific polymorphisms associated with consensus regulatory region promoter elements. In order to evaluate the potential function of allele-specific elements, HLA-DQB1 transcripts and in vivo footprinting of the DQB1 promoter were studied in human cell lines inducible for HLA class II expression. In the heterozygous melanoma...
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