Article
Assessment of collagen type II induced arthritis in mice by whole blood chemiluminescence.
Autoimmunity - 1 Jan 1994
Miesel R, Dietrich A, Ulbrich N, Kroeger H, Mitchison N A
Abstract excerpt
Lucigenin-enhanced chemiluminescence can be measured in 100 microliters samples of whole, unseparated mouse blood. A procedure for doing so is here described in detail, using a standard clinical luminometer. The assay measures the TPA-induced oxidative burst from granulocytes and macrophages, whi...
Topics
- Acridines
- Animals
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Cattle
- Collagen
- Crosses, Genetic
- Disease Models, Animal
- Drug Evaluation, Preclinical
- Genetic Predisposition to Disease
- Haplotypes
- Luminescent Measurements
- Male
- Mice
- Mice, Inbred DBA
- Reproducibility of Results
- Respiratory Burst