Article
F <sub>2</sub> -Isoprostanes as markers of oxidative stress <i>in vivo</i> : An overview
1 Jan 2005
Abstract excerpt
The isoprostanes are a unique series of prostaglandin-like compounds formed in vivo via a non-enzymatic mechanism involving the free radical-initiated peroxidation of arachidonic acid. This article summarizes selected aspects regarding current knowledge of these compounds and their value as markers of oxidative injury. Novel aspects related to the biochemistry of isoprostane formation are discussed and methods by...
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