Article

A Complete Freund’s Adjuvant-Induced Murine Model as an Experimental Platform to Explore Systemic Inflammation in Rheumatoid Arthritis

2026-01-20

Abstract excerpt

<title>Abstract</title> <p> <bold>Introduction:</bold> Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease that compromises joint integrity and triggers extra-articular manifestations associated with oxidative distress and systemic inflammation. This study analysed the onset of inflammation in the CFA-induced arthritis model by characterising peripheral molecular and tissue changes to elucidate...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5d7539c1-8ac0-5bc3-8124-3093cd3ca042
DOI: 10.21203/rs.3.rs-8523680/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Complete Freund’s Adjuvant-Induced Murine Model as an Experimental Platform to Explore Systemic Inflammation in Rheumatoid ArthritisDOI 10.21203/rs.3.rs-8523680/v1Read

The Therapeutic Potential of Phytochemicals Unlocks New Avenues in the Management of Rheumatoid ArthritisSemantic proximity Read

Sulforaphane Modulates Joint Inflammation in a Murine Model of Complete Freund's Adjuvant-Induced Mono-Arthritis.Semantic proximity Read

Nerolidol: a potential approach in rheumatoid arthritis through reduction of TNF-α, IL-1β, IL-6, NF-Kβ, COX-2 and anti-oxidant effect in CFA-induced arthritic modelSemantic proximity Read

Rheumatoid arthritis: the role of reactive oxygen species in disease development and therapeutic strategies.Semantic proximity Read

One year in review 2016: pathogenesis of rheumatoid arthritis.Semantic proximity Read

Model answers: Rational application of murine models in arthritis research.Semantic proximity Read

[Serious organ damage and intractable clinical conditions in rheumatic and connective tissue disease--progress in pathophysiology and treatment. Topics: I. Damage to important organs whose early treatment makes a big difference; 9. Rheumatoid arthritis: the progress of pathology and therapeutic strategy].Semantic proximity Read

Evidence of an Allostatic Response by Intestinal Tissues Following Induction of Joint InflammationSemantic proximity Read

Quantitative Proteomic Analysis of Bi Zhong Xiao Decoction Against Collagen-induced Arthritis Rats in the Early and Late StagesSemantic proximity Read

Endothelial Dysfunction and Extra-Articular Neurological Manifestations in Rheumatoid ArthritisSemantic proximity Read

Equisetum diffusummethanol extract attenuates RA by modulating the expression of key biomarkers like COX-2, TNF-α, IL-6, PPAR-γ, and Iκβ in Adjuvant-induced rats.Semantic proximity Read

Arthritis Critically Dependent on Innate Immune System PlayersSemantic proximity Read