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Article

Mechanisms of allele-selective down-regulation of HLA class I in Burkitt's lymphoma.

International journal of cancer - 4 Jul 1995

Imreh M P, Zhang Q J, de Campos-Lima P O, Imreh S, Krausa P, Browning M, Klein G, Masucci M G

Abstract excerpt

Burkitt lymphomas (BL) that arise in HLA-AII-positive individuals are characterized by selective loss/down-regulation of the HLA AII polypeptide. We have investigated the molecular basis of such down-regulation by comparing 5 pairs of BL lines and Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines (LCL) derived from the normal B cells of the same individuals. The presence of apparently intact HLA AII...

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Identifiers

PMID: 7601573
DOI: 10.1002/ijc.2910620117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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