Article
Immune escape by Epstein-Barr virus (EBV) carrying Burkitt's lymphoma: in vitro reconstitution of sensitivity to EBV-specific cytotoxic T cells.
International immunology - 1 Nov 1992
Masucci M G, Zhang Q J, Gavioli R, De Campos-Lima P O, Murray R J, Brooks J, Griffin H, Ploegh H, Rickinson A B
Abstract excerpt
Epstein-Barr virus (EBV) positive Burkitt's lymphoma (BL) cells are markedly less sensitive to EBV-specific cytotoxic T cell (CTL) recognition than EBV-transformed lymphoblastoid cell lines of normal B cell origin. Three features of the BL cell phenotype might contribute to this reduced susceptib...
Topics
- Antigens, CD
- Antigens, Neoplasm
- Antigens, Surface
- Antigens, Viral
- B-Lymphocytes
- Burkitt Lymphoma
- CD58 Antigens
- Cell Line, Transformed
- DNA-Binding Proteins
- Epstein-Barr Virus Nuclear Antigens
- Gene Expression Regulation, Neoplastic
- HLA-A Antigens
- HLA-A11 Antigen