Article
Restoration of endogenous antigen processing in Burkitt's lymphoma cells by Epstein-Barr virus latent membrane protein-1: coordinate up-regulation of peptide transporters and HLA-class I antigen expression.
European journal of immunology - 1 May 1995
Rowe M, Khanna R, Jacob C A, Argaet V, Kelly A, Powis S, Belich M, Croom-Carter D, Lee S, Burrows S R
Abstract excerpt
Group I Burkitt lymphoma (BL) lines retaining the original BL tumor cell phenotype are unable to present endogenously expressed antigens to HLA class I-restricted cytotoxic T cells (CTL) but can be recognized if the relevant HLA class I/peptide epitope complex is reconstituted at the cell surface...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Amino Acid Sequence
- Antigen Presentation
- Antigens
- Antigens, Viral
- Burkitt Lymphoma
- Cell Transformation, Viral
- Cysteine Endopeptidases
- DNA-Binding Proteins
- Epstein-Barr Virus Nuclear Antigens