Article
Mouse ubiquitous mitochondrial creatine kinase: gene organization and consequences from inactivation in mouse embryonic stem cells.
DNA and cell biology - 1 Jun 1995
Steeghs K, Peters W, Brückwilder M, Croes H, Van Alewijk D, Wieringa B
Abstract excerpt
Individual members of the creatine kinase isoenzyme family (CK; EC 2.7.3.2), which play a prominent role in energy homeostasis, are encoded by four separate nuclear genes. We have isolated and characterized the complete mouse UbCKmit gene, the product of which is ubiquitously expressed and is loc...
Topics
- Animals
- Base Sequence
- Cells, Cultured
- Creatine Kinase
- Embryonic and Fetal Development
- Enzyme Activation
- Gene Expression Regulation, Developmental
- Gene Expression Regulation, Enzymologic
- Mice
- Mitochondria
- Molecular Sequence Data
- Mutation
- Sequence Alignment
- Stem Cells