Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation of the gene HEM4 encoding uroporphyrinogen III synthase in Saccharomyces cerevisiae.

Yeast (Chichester, England) - 30 Apr 1995

Amillet J M, Labbe-Bois R

Abstract excerpt

We have isolated a genomic DNA fragment that complements the yeast temperature-sensitive cyt mutation, causing respiratory deficiency and accumulation of porphyrins (Sugimura et al., 1966). Partial DNA sequencing of the complementing region and search for similarity in the DNA and protein databases revealed that (1) the gene had been previously isolated by complementation of the mutation ts2326 (Langgut et al.,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA, Fungal
Share to Genes, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Complementation Test

Share to Molecular Sequence Data

Share to Mutation

Share to Saccharomyces cerevisiae

Source

Identifiers

PMID: 7597845
DOI: 10.1002/yea.320110504

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isolation of the gene HEM4 encoding uroporphyrinogen III synthase in Saccharomyces cerevisiae.PMID 7597845Read ↗

Cloning and identification of HEM14, the yeast gene for mitochondrial protoporphyrinogen oxidase.Semantic proximity Read ↗

Identification of amino acid changes affecting yeast uroporphyrinogen decarboxylase activity by sequence analysis of hem12 mutant alleles.Semantic proximity Read ↗

Characterization of the Saccharomyces cerevisiae ERG26 gene encoding the C-3 sterol dehydrogenase (C-4 decarboxylase) involved in sterol biosynthesis.Semantic proximity Read ↗

A systematic analysis of the mutations of the uroporphyrinogen III synthase gene in congenital erythropoietic porphyria.Semantic proximity Read ↗

Identification of mutations in the uroporphyrinogen III synthase gene in a Thai girl patient with congenital erythropoietic porphyria.Semantic proximity Read ↗

Isolation of a cDNA encoding the human homolog of COX17, a yeast gene essential for mitochondrial copper recruitment.Semantic proximity Read ↗

Crystal structure of human uroporphyrinogen III synthase.Semantic proximity Read ↗

Isolation and functional characterization of mutant ferrochelatases in Saccharomyces cerevisiae.Semantic proximity Read ↗

Isolation and characterization of a new mutant of Saccharomyces cerevisiae with altered synthesis of 5-aminolevulinic acid.Semantic proximity Read ↗

A novel allele of HAP1 causes uninducible expression of HEM13 in Saccharomyces cerevisiae.Semantic proximity Read ↗

Saccharomyces cerevisiae mutants defective in heme biosynthesis as a tool for studying the mechanism of phototoxicity of porphyrins.Semantic proximity Read ↗

Characterization of COX17, a yeast gene involved in copper metabolism and assembly of cytochrome oxidase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.