Article
COOH-terminal sequence motifs target the T cell protein tyrosine phosphatase to the ER and nucleus.
The Journal of cell biology - 1 Nov 1995
Lorenzen J A, Dadabay C Y, Fischer E H
Abstract excerpt
The noncatalytic domain of the human T cell protein tyrosine phosphatase (TCPTP) is alternatively spliced to generate a 45-kD form, p45TC, and a 48-kD form, p48TC (Champion-Arnaud et al., 1991; Mosinger et al., 1992). This manuscript concerns structural motifs in the noncatalytic segment of the e...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- CHO Cells
- Cell Fractionation
- Cell Nucleus
- Cricetinae
- Endoplasmic Reticulum
- Fluorescent Antibody Technique
- Gene Expression
- Humans
- Kidney
- Molecular Sequence Data
- Mutation
- Protein Tyrosine Phosphatase, Non-Receptor Type 2
- Protein Tyrosine Phosphatases
- Rats