Article
Pathogenesis of defined invasion mutants of Yersinia enterocolitica in a BALB/c mouse model of infection.
Infection and immunity - 1 Dec 1995
Pepe J C, Wachtel M R, Wagar E, Miller V L
Abstract excerpt
It has been hypothesized for many years that the ability of Yersinia spp. to invade tissue culture cells is reflective of their ability to penetrate the intestinal epithelium and that this capacity is an important aspect of the disease process. Three different genes from Yersinia spp. that are involved in the tissue culture invasion phenotype have been identified: inv, ail, and yadA. It was previously shown that...
Topics
- Animals
- Antibodies, Bacterial
- CHO Cells
- Cricetinae
- Disease Models, Animal
- Female
- Immunohistochemistry
- Mice
- Mice, Inbred BALB C
- Mutation
- Peyer's Patches
- Virulence