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Article

Yersinia enterocolitica invasin: a primary role in the initiation of infection.

Proceedings of the National Academy of Sciences of the United States of America - 15 Jul 1993

Pepe J C, Miller V L

Abstract excerpt

The ability to invade the intestinal epithelium of mammals is an essential virulence determinant of Yersinia enterocolitica. The chromosomally encoded Y. enterocolitica 8081v invasion gene, inv, was disrupted to assess its role in pathogenesis. The inv mutant (JP273v) was approximately 80-fold less invasive than wild type for cultured epithelial cells. When mice were infected intragastrically, up to 10(7) fewer...

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Identifiers

PMID: 8341658
DOI: 10.1073/pnas.90.14.6473
PMCID: PMC46954

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Source receipt: pubmed, retrieved 7 Sept 2026.

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