Article
The biological role of invasin during a Yersinia enterocolitica infection.
Infectious agents and disease - 1 Aug 1993
Pepe J C, Miller V L
Abstract excerpt
Epidemiological data suggest that the ability to invade the intestinal epithelium of mammals is an essential virulence determinant of Yersinia enterocolitica. The chromosomally encoded Y. enterocolitica 8081v invasion gene, inv, was disrupted to assess its role in pathogenesis. The inv mutant was unable to invade cultured epithelial cells as efficiently as wild type. Furthermore, when mice were infected...
Topics
- Adhesins, Bacterial
- Animals
- Bacterial Proteins
- Mice
- Mice, Inbred BALB C
- Mutation
- Virulence
- Yersinia Infections
- Yersinia enterocolitica