Article
Cellular internalization in the absence of invasin expression is promoted by the Yersinia pseudotuberculosis yadA product.
Infection and immunity - 1 Sept 1993
Yang Y, Isberg R R
Abstract excerpt
The Yersinia pseudotuberculosis invasin protein is able to promote bacterial penetration into mammalian cells. Insertion mutations that eliminate production of this protein show residual internalization that is dependent on the presence of the Yersinia virulence plasmid. An enrichment procedure was used to isolate molecular clones containing regions of the virulence plasmid that confer this low-level uptake on Y....
Topics
- Adhesins, Bacterial
- Bacterial Adhesion
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Base Sequence
- Genes, Bacterial
- Humans
- Molecular Sequence Data
- Mutation
- Plasmids
- Tumor Cells, Cultured
- Virulence
- Yersinia pseudotuberculosis