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Article

Effect of TGF-beta on differentiated organoids of the colon carcinoma cell line LIM 1863.

Immunology and cell biology - 1 Jun 1995

Hayward I P, Whitehead R H, Ward L, Gianello R, Dempsey P, Bates R, Burns G F

Abstract excerpt

The LIM 1863 colon carcinoma cell line grows in suspension as morphologically and functionally organized organoids in serum-containing medium. Addition of TGF-beta caused the organoids to adhere and inhibited DNA synthesis. A 20 min incubation with TGF-beta was sufficient to induce adherence and this could be inhibited by cycloheximide. The adhesion and DNA synthesis inhibition were demonstrated to be separate...

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Source

Identifiers

PMID: 7590899
DOI: 10.1038/icb.1995.41

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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