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Article

Effect of TGF-beta on differentiated organoids of the colon carcinoma cell line LIM 1863.

Immunology and cell biology - 1 Jun 1995

Hayward I P, Whitehead R H, Ward L, Gianello R, Dempsey P, Bates R, Burns G F

Abstract excerpt

The LIM 1863 colon carcinoma cell line grows in suspension as morphologically and functionally organized organoids in serum-containing medium. Addition of TGF-beta caused the organoids to adhere and inhibited DNA synthesis. A 20 min incubation with TGF-beta was sufficient to induce adherence and...

Topics

Carcinoma
Cell Adhesion
Cell Differentiation
Colonic Neoplasms
DNA
Humans
Integrins
Organ Culture Techniques
Phenotype
Transforming Growth Factor beta
Tumor Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7590899
DOI: 10.1038/icb.1995.41

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7590899-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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