Article
Enhanced expression of myogenic regulatory genes in aging skeletal muscle.
Experimental cell research - 1 Nov 1995
Musarò A, Cusella De Angelis M G, Germani A, Ciccarelli C, Molinaro M, Zani B M
Abstract excerpt
MyoD, myogenin, myf-5, and MRF4, belonging to the family of basic helix-loop-helix (bHLH) myogenic regulatory factors (MRFs), control muscle cell differentiation, in concert with other transcription factors such as MEF-2, yet their role in age-related skeletal muscle alteration has not been addre...
Topics
- Aging
- Animals
- Cell Differentiation
- DNA-Binding Proteins
- Gene Expression
- Hypertrophy
- Immunohistochemistry
- Male
- Mice
- Mice, Inbred C57BL
- Muscle Fibers, Skeletal
- Muscle Proteins
- Muscle, Skeletal
- MyoD Protein
- Myogenic Regulatory Factor 5
- Myogenic Regulatory Factors
- Myogenin
- Myosins
