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Article

Anti-DNA IgA autoantibodies are spontaneously generated in mouse Peyer's patches.

Immunology - 1 Oct 1998

Shimoda M, Inoue Y, Ametani A, Fujiwara J, Tsuji N M, Kurisaki J, Azuma N, Kanno C

Abstract excerpt

IgA antibodies in the mucosal immune system are produced specifically to environmental antigens such as virus and bacteria, and possibly to some food components, which will provide a potential luminal antigen, DNA. To study the immune response to DNA in the gut, we established B-cell hybridomas producing IgA monoclonal antibodies (mAb) from Peyer's patches (PP) of non-immunized, non-autoimmune, specific...

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Identifiers

PMID: 9824476
DOI: 10.1046/j.1365-2567.1998.00582.x
PMCID: PMC1364305

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