Article
Studying autoimmunity by in vivo RNA interference.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Kissler Stephan
Abstract excerpt
The occurrence of autoimmunity is strongly associated with multiple gene variants that predispose individuals to disease. The identification of the gene polymorphisms that modulate disease susceptibility is key to our understanding of disease etiology and pathogenesis. While genetic studies in humans have uncovered several associations and have provided possible candidate genes for further study, the use of...
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