Article
Donor specific bone marrow cells suppress lymphocyte reactivity to donor antigens and differentially modulate TH1 and TH2 cytokine gene expression in the responder cell population.
Transplant immunology - 1 Jun 1995
Lagoo-Deenadayalan S, Lagoo A S, Lemons J A, Lorenz H M, Bass J D, McDaniel D O, Hardy K J, Barber W H
Abstract excerpt
Previous studies have shown that post-transplantation infusion of donor specific bone marrow following a non-specific potent immunosuppressive agent such as antilymphocyte globulin (ALG) can significantly enhance graft survival compared to ALG alone. This enhancement remains variable and is thoug...
Topics
- Bone Marrow
- Bone Marrow Cells
- Bone Marrow Transplantation
- CD3 Complex
- Cell Division
- Cells, Cultured
- Cryopreservation
- Cytokines
- Fibroblast Growth Factor 1
- Granulocyte-Macrophage Colony-Stimulating Factor