Article
Renal allograft-infiltrating lymphocytes. A prospective analysis of in vitro growth characteristics and clinical relevance.
Transplantation - 1 Feb 1992
Kirk A D, Ibrahim M A, Bollinger R R, Dawson D V, Finn O J
Abstract excerpt
One-hundred consecutive human renal allograft Tru-cut needle biopsies were studied for in vitro proliferation of T lymphocytes under restrictive culture conditions containing low-dose recombinant interleukin 2. Each biopsy was entered into a blinded code and evaluated prospectively for visual evidence of growth at 24 hr and for sustained growth. Those T cell populations exhibiting sustained growth were then...
Topics
- CD4 Antigens
- CD8 Antigens
- Epitopes
- Female
- Graft Rejection
- Humans
- Interleukin-2
- Kidney Transplantation
- Lymphocyte Activation
- Lymphokines
- Male
- Phenotype