Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chimerism and Tolerance Without GVHD or Engraftment Syndrome in HLA-Mismatched Combined Kidney and Hematopoietic Stem Cell Transplantation

7 Mar 2012

Abstract excerpt

The toxicity of chronic immunosuppressive agents required for organ transplant maintenance has prompted investigators to pursue approaches to induce immune tolerance. We developed an approach using a bioengineered mobilized cellular product enriched for hematopoietic stem cells (HSCs) and tolerogenic graft facilitating cells (FCs) combined with nonmyeloablative conditioning; this approach resulted in engraftment,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematopoietic Stem Cell Transplantation
Share to Renal Transplantation Outcomes and Treatments
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22399264
DOI: 10.1126/scitranslmed.3003509

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chimerism and Tolerance Without GVHD or Engraftment Syndrome in HLA-Mismatched Combined Kidney and Hematopoietic Stem Cell TransplantationPMID 22399264Read ↗

Chimerism-Based Tolerance to Kidney Allografts in Humans: Novel Insights and Future PerspectivesSemantic proximity Read ↗

Stable Multilineage Chimerism without Graft versus Host Disease Following Nonmyeloablative Haploidentical Hematopoietic Cell TransplantationSemantic proximity Read ↗

Chimerism in the Realm of Hematopoietic Stem Cell Transplantation for Non-malignant Disorders—A PerspectiveSemantic proximity Read ↗

Chimerism-based Tolerance Induction in Clinical Transplantation: Its Foundations and MechanismsSemantic proximity Read ↗

Mixed allogeneic chimerism and tolerance to composite tissue allograftsSemantic proximity Read ↗

Robust tolerance to fully allogeneic islet transplants achieved by chimerism with minimal conditioning.Semantic proximity Read ↗

Establishment of stable multilineage hematopoietic chimerism and donor-specific tolerance without irradiation.Semantic proximity Read ↗

Hematopoietic chimerism and central tolerance created by peripheral-tolerance induction without myeloablative conditioningSemantic proximity Read ↗

Intentional induction of mixed chimerism and achievement of antitumor responses after nonmyeloablative conditioning therapy and HLA-matched donor bone marrow transplantation for refractory hematologic malignancies.Semantic proximity Read ↗

Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapySemantic proximity Read ↗

Detection of impending graft rejection and relapse by lineage-specific chimerism analysis.Semantic proximity Read ↗

Mixed Chimerism and Transplantation ToleranceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.