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Article

Induction of suppressive allogeneic regulatory T cells via rabbit antithymocyte polyclonal globulin during homeostatic proliferation in rat kidney transplantation.

Transplant international : official journal of the European Society for Organ Transplantation - 1 Jan 2015

Valdez-Ortiz Rafael, Bestard Oriol, Llaudó Inés, Franquesa Marcella, Cerezo Gema, Torras Joan, Herrero-Fresneda Inmaculada, Correa-Rotter Ricardo, Grinyó Josep M

Abstract excerpt

Experimental studies have shown that rabbit antithymocyte polyclonal globulin (ATG) can expand human CD4+CD25++Foxp3+ cells (Tregs). We investigated the major biological effects of a self-manufactured rabbit polyclonal anti-rat thymoglobulin (rATG) in vitro, as well as its effects on different peripheral T-cell subsets. Moreover, we evaluated the allogeneic suppressive capacity of rATG-induced Tregs in an...

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PMID: 25208307
DOI: 10.1111/tri.12448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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