Article
Transcriptional Targeting Approaches in Cardiac Gene Transfer Using AAV Vectors
30 Oct 2023
Abstract excerpt
Cardiac-targeted transgene delivery offers new treatment opportunities for cardiovascular diseases, which massively contribute to global mortality. Restricted gene transfer to cardiac tissue might protect extracardiac organs from potential side-effects. This could be mediated by using cis-regulatory elements, including promoters and enhancers that act on the transcriptional level. Here, we discuss examples of...
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