Article
Oligogenic determination of morphine analgesic magnitude: a genetic analysis of selectively bred mouse lines.
Behavior genetics - 1 Jul 1995
Mogil J S, Flodman P, Spence M A, Sternberg W F, Kest B, Sadowski B, Liebeskind J C, Belknap J K
Abstract excerpt
Two ongoing selective breeding projects have produced mice that display divergent analgesic responses to morphine. These two projects have selected for similar phenotypes: high and low levorphanol analgesia (HAR/LAR lines; Portland, OR) and high and low swim stress-induced analgesia (HA/LA lines; Jastrzebiec, Poland). Evidence suggests genetic commonalities between mice of the two projects. Using a Mendelian...
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