Article
Heritability of symptoms in the neuroma model of neuropathic pain: replication and complementation analysis.
Pain - 1 Aug 2005
Devor Marshall, Del Canho Sonia, Raber Pnina
Abstract excerpt
Applying genetic selection pressure to an outbred population of albino rats, we have derived lines that show consistently high versus low pain phenotype in the neuroma model of neuropathic pain. Trait segregation developed rapidly, replicating earlier observations using this methodology. The resulting novel selection lines, designated nHA and nLA, share a common genetic background but have dramatically...
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