Article
Suicidal behaviors and the tryptophan hydroxylase gene.
Archives of general psychiatry - 1 Oct 1995
Abbar M, Courtet P, Amadéo S, Caer Y, Mallet J, Baldy-Moulinier M, Castelnau D, Malafosse A
Abstract excerpt
BACKGROUND: To determine whether the tryptophan hydroxylase gene (ie, the gene that codes for the rate-limiting enzyme in the metabolic pathway of serotonin) may be a susceptibility factor for suicidal behavior. METHODS: Genotypic and allelic frequencies at a polymorphic Ava II restriction site were revealed with the use of the complementary DNA tryptophan hydroxylase probe C2-38 in 62 suicide attempters. The...
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