Article
Suicidal behaviors and the tryptophan hydroxylase gene.
Archives of general psychiatry - 1 Oct 1995
Abbar M, Courtet P, Amadéo S, Caer Y, Mallet J, Baldy-Moulinier M, Castelnau D, Malafosse A
Abstract excerpt
BACKGROUND: To determine whether the tryptophan hydroxylase gene (ie, the gene that codes for the rate-limiting enzyme in the metabolic pathway of serotonin) may be a susceptibility factor for suicidal behavior. METHODS: Genotypic and allelic frequencies at a polymorphic Ava II restriction site w...
Topics
- Alleles
- Female
- Genotype
- Humans
- Male
- Mental Disorders
- Middle Aged
- Polymorphism, Genetic
- Psychiatric Status Rating Scales
- Risk Factors
- Serotonin
- Suicide, Attempted
- Tryptophan Hydroxylase
