Article
Involvement of yeast carboxy-terminal domain kinase I (CTDK-I) in transcription elongation in vivo.
Gene - 4 Apr 2001
Jona G, Wittschieben B O, Svejstrup J Q, Gileadi O
Abstract excerpt
Yeast cells lacking transcription elongation factor genes such as PPR2 (TFIIS) and ELP (Elongator) are viable and show deleterious phenotypes only when transcription is rendered less effective by RNA polymerase mutations or by decreasing nucleotide pools. Here we demonstrate that deletion of the CTK1 gene, encoding the kinase subunit of RNA polymerase II carboxy-terminal domain kinase I (CTDK-I), is synthetically...
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