Article
Human cyclin K, a novel RNA polymerase II-associated cyclin possessing both carboxy-terminal domain kinase and Cdk-activating kinase activity.
Molecular and cellular biology - 1 Jul 1998
Edwards M C, Wong C, Elledge S J
Abstract excerpt
The gene coding for human cyclin K was isolated as a CPR (cell-cycle progression restoration) gene by virtue of its ability to impart a Far- phenotype to the budding yeast Saccharomyces cerevisiae and to rescue the lethality of a deletion of the G1 cyclin genes CLN1, CLN2, and CLN3. The cyclin K...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- CDC2 Protein Kinase
- Cell Line
- Coenzymes
- Cyclin-Dependent Kinase 8
- Cyclin-Dependent Kinases
- Cyclins
- Drosophila Proteins
- Drosophila melanogaster
- G1 Phase
- Glutathione Transferase
- Humans
- Insecta
- Mice
- Mice, Inbred C57BL
- Molecular Sequence Data