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Article

Human cyclin K, a novel RNA polymerase II-associated cyclin possessing both carboxy-terminal domain kinase and Cdk-activating kinase activity.

Molecular and cellular biology - 1 Jul 1998

Edwards M C, Wong C, Elledge S J

Abstract excerpt

The gene coding for human cyclin K was isolated as a CPR (cell-cycle progression restoration) gene by virtue of its ability to impart a Far- phenotype to the budding yeast Saccharomyces cerevisiae and to rescue the lethality of a deletion of the G1 cyclin genes CLN1, CLN2, and CLN3. The cyclin K gene encodes a 357-amino-acid protein most closely related to human cyclins C and H, which have been proposed to play a...

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Identifiers

PMID: 9632813
DOI: 10.1128/MCB.18.7.4291
PMCID: PMC109013

Genes

CLN3

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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