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Article

Activation of the transcriptional regulator XylR of Pseudomonas putida by release of repression between functional domains.

Molecular microbiology - 1 Apr 1995

Fernández S, de Lorenzo V, Pérez-Martín J

Abstract excerpt

In the presence of toluene, xylenes and other structural analogues, the regulatory protein XylR, of the family of transcriptional regulators which act in concert with the sigma 54 factor, activate the promoter Pu of the TOL (toluene degradation) plasmid pWWO of Pseudomonas putida. Amino acid changes Val-219-Asp and Ala-220-Pro, introducing a proline kink at the hinge region between the N-terminal A domain and the...

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Identifiers

PMID: 7565083
DOI: 10.1111/j.1365-2958.1995.tb02293.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation of the transcriptional regulator XylR of Pseudomonas putida by release of repression between functional domains.PMID 7565083Read ↗

The role of the interdomain B linker in the activation of the XylR protein of Pseudomonas putida.Semantic proximity Read ↗

Genetic evidence of separate repressor and activator activities of the XylR regulator of the TOL plasmid, pWW0, of Pseudomonas putida.Semantic proximity Read ↗

Emergence of novel functions in transcriptional regulators by regression to stem protein types.Semantic proximity Read ↗

VTR expression cassettes for engineering conditional phenotypes in Pseudomonas: activity of the Pu promoter of the TOL plasmid under limiting concentrations of the XylR activator protein.Semantic proximity Read ↗

A la carte transcriptional regulators: unlocking responses of the prokaryotic enhancer-binding protein XylR to non-natural effectors.Semantic proximity Read ↗

Activation of the Pseudomonas TOL plasmid upper pathway operon. Identification of binding sites for the positive regulator XylR and for integration host factor protein.Semantic proximity Read ↗

Design of new promoters and of a dual-bioreporter based on cross-activation by the two regulatory proteins XylR and HbpR.Semantic proximity Read ↗

Broadening the signal specificity of prokaryotic promoters by modifying cis-regulatory elements associated with a single transcription factor.Semantic proximity Read ↗

An operator binding-negative mutation of Xyl repressor from Bacillus subtilis is trans dominant in Bacillus megaterium.Semantic proximity Read ↗

A T7 RNA polymerase-based system for the construction of Pseudomonas strains with phenotypes dependent on TOL-meta pathway effectors.Semantic proximity Read ↗

An upstream XylR- and IHF-induced nucleoprotein complex regulates the sigma 54-dependent Pu promoter of TOL plasmid.Semantic proximity Read ↗

Cross talk between catabolic pathways in Pseudomonas putida: XylS-dependent and -independent activation of the TOL meta operon requires the same cis-acting sequences within the Pm promoter.Semantic proximity Read ↗

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