Article
The alpha-dendrotoxin footprint on a mammalian potassium channel.
The Journal of biological chemistry - 20 Oct 1995
Tytgat J, Debont T, Carmeliet E, Daenens P
Abstract excerpt
alpha-Dendrotoxin, a 59-amino acid basic peptide from the venom of Dendroaspis angusticeps (green mamba snake), potently blocks some but not all voltage-dependent potassium channels. Here we have investigated the relative contribution of the individual alpha-subunits constituting functional Kv1.1...
Topics
- Amino Acid Sequence
- Animals
- Binding Sites
- Elapid Venoms
- Female
- Molecular Sequence Data
- Mutation
- Oocytes
- Potassium Channel Blockers
- Potassium Channels
- Xenopus laevis