Article
The alpha-dendrotoxin footprint on a mammalian potassium channel.
The Journal of biological chemistry - 20 Oct 1995
Tytgat J, Debont T, Carmeliet E, Daenens P
Abstract excerpt
alpha-Dendrotoxin, a 59-amino acid basic peptide from the venom of Dendroaspis angusticeps (green mamba snake), potently blocks some but not all voltage-dependent potassium channels. Here we have investigated the relative contribution of the individual alpha-subunits constituting functional Kv1.1 potassium channels to alpha-dentroxin binding. Three residues critical for alpha-dentrotoxin binding and located in...
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